|Series||Experimental biology and medicine -- v. 3, Experimental biology and medicine -- vol. 3|
|Contributions||Baumgartner, H. R., Haanen, C.,, Jürgens, J.,|
|LC Classifications||QP97 P53|
|The Physical Object|
|Number of Pages||240|
Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from world experts from 18 xcientia.com award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation. Platelets, Haemostasis and Inflammation (Cardiac and Vascular Biology) [Andreas Zirlik, Christoph Bode, Meinrad Gawaz] on xcientia.com *FREE* shipping on qualifying offers. The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosisAuthor: Andreas Zirlik. “A focus of the book is on the link between haemostasis and inflammation, and the roles that platelets play in both. It also aims to describe recent advances in basic science and early results of clinical trials. The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies.
Hemostasis or haemostasis is a process to prevent and stop bleeding, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage). It is the first stage of wound healing. This involves coagulation, blood changing from a liquid to a gel. Intact blood vessels are central to moderating blood's tendency to form clots. Platelets, also called “thrombocytes”, are blood cells whose function (along with the coagulation factors) is to stop bleeding. Platelets have no nucleus: they are fragments of cytoplasm which are derived from the megakaryocytes of the bone marrow, and then enter the circulation. These unactivated platelets are biconvex discoid structures shaped like a lens, 2–3 µm in greatest diameter. In he received the International Society on Thrombosis and Haemostasis (ISTH) Esteemed Career Award. Dr. Michelson has been an invited participant in numerous National Institutes of Health working groups, international workshops and consensus conferences. He is the co-organizer and co-chair of the biennial International Platelets Symposium Price: $ Note: Citations are based on reference standards. However, formatting rules can vary widely between applications and fields of interest or study. The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied.
The platelets rush to the site of damage and form clots to repair the damage. The activated platelets stick together to form a platelet plug which in turn activates the coagulation factor. Vitamin K is beneficial for the proper functioning of the coagulation factor. Let us have an overview of platelets and coagulation. Also Read: Blood Coagulation. Platelets interact with the coagulation factors in a complex way to arrest bleeding or generate thrombi. Recently, the platelet's relationship to endothelial alteration and atheroma production has received renewed attention. At present, tests of platelet function better define “hypocoagulable” rather than “hypercoagulable” xcientia.com by: Platelets have a critical role in haemostasis when vessel wall is injured. Platelet receptors are involved in sequence in this process by slowing platelets down via GPIb/von Willebrand factor to bring them into contact with exposed collagen, then activating them via GPVI to release granule contents and express integrins in a matrix protein binding xcientia.com by: Nov 02, · Blood #5, Platelets & Hemostasis - Physiology 1. Platelets small granulated Non-nucleated round or oval 2 – 4 µ in diameter mm³/ – life span average 8 days detached bits from megakaryocyte.